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Author

  • The Perth Group

  • Eleni Papadopulos

  • Valendar Turner

  • John M. Papadimitriou

  • David Causer

  • Bruce Hedland-Thomas

  • Barry Page

Publisher

  • Genetica

Category

  • CD4+

Topic

  • CD4+ Reliability

  • T4 Cells

  • T Lymphocytes

  • AZT

  • Zidovudine

  • Immunodeficiency

  • Pneumonia

  • Oxidative stress

Article Type

  • Editorial article

Publish Year

  • 1995

Meta Description

  • The content critically analyzes the HIV-T4-CELL-AIDS hypothesis, questioning the link between T4 cell decrease and AIDS, and exploring alternative causes.

Summary

  • This is a critical analysis of the HIV-T4-CELL-AIDS hypothesis. The authors question the widely accepted theory that HIV causes AIDS. They argue that the evidence supporting this theory is based on the relationship between a positive HIV antibody test and AIDS. However, they raise concerns about the accuracy of the test and the lack of a gold standard for verifying its sensitivity and specificity. The authors also discuss the role of T4 lymphocytes in the immune response and highlight studies that suggest T cells have both suppressive and helper activities. They conclude that further research is needed to fully understand the relationship between HIV, T4 cells, and AIDS.

Meta Tag

  • HIV

  • AIDS

  • T4 lymphocytes

  • Oxidative stress

  • CD4 antigen

  • CD8 antigen

  • Immunodeficiency

  • IL-2

  • Phenotype

  • Chemotherapy

  • Zidovudine

  • Opportunistic Pneumonias

Featured Image

Featured Image Alt Tag

  • Keyword of the image

Eleni Papadopulos-Eleopulos,1 Valendar F.Turner,2 John M. Papadimitriou,3 David Causer,1 Bruce Hedland-Thomas,1 & Barry Page1
1: Department of Medical Physics, 2: Department of Emergency Medicine, Royal Perth Hospital, Perth, Western Australia; 3: Department of Pathology, University of Western Australia.
Genetica 95: 5-24, 1995

Author Tag

Publisher Tag

Topic Tag

  • Eleni Papadopulos

  • Valendar Turner

  • John M. Papadimitriou

  • David Causer

  • Bruce Hedland-Thomas

  • Barry Page

  • Genetica

  • CD4+

    • T4 Cells

    • T Lymphocytes

View file
nameHIVT4CellAIDS.pdf

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Knowledge is one. Its division into subjects is a concession to human weakness.
Halford John Mackinder

...

We would like to thank all our colleagues and especially Richard Fox, Livo Mina, Alun Dufty, Gary James, Iris Peter, the staff of the Royal Perth Hospital Library and the clerical staff of the Department of Medical Physics. We also thank Harvey Bialy, Udo Schuklenk, Charles Thomas, Gordon Stewart, Michael Verney Elliot and Joan Shenton for continual encouragement, and Peter Duesberg for inviting us to submit this paper to Genetica.

References

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