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Author

  • Mark Craddock

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  • CD4+

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  • CD4+ Reliability

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  • Editorial Article

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  • Mark Craddock critiques Ho & Shaw's papers on viral interaction with the immune system, calling their methods and conclusions inaccurate and misleading.

Summary

  • The content is an analysis of two papers by Ho and Shaw, which the author considers to be of poor quality. The author questions the models constructed by the researchers to understand the interaction between a virus and the immune system. They criticize the assumptions made and the accuracy of the measurements. The author also highlights the need for more advanced mathematical techniques in analyzing this type of data. Overall, the author concludes that the papers are not reliable and lack a proper understanding of the immune system.

Meta Tag

  • Mark Craddock

  • Ho & Shaw Papers

  • Viral Interaction

  • Immune System

  • Mathematical Techniques

  • Regression Analysis

  • Viral Clearance

  • Differential Equations

  • Viral Production

  • Geometric Mean

  • T Cells

  • Exponential Growth

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By Mark Craddock
School of Mathematics
University of New South Wales, Australia

...

I have completed a preliminary analysis of the papers by Ho and Shaw which appeared in Nature, January 12, 1995. My considered opinion is that they are total rubbish. I seriously doubt that the two groups really have any idea what they are doing when they construct their supposed models of the interaction of the virus and the immune system. The models when analysed properly do not do what they think they do.

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