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Eleni Papadopulos-Eleopulos (1), Valendar F.Turner (2), John M. Papadimitriou (3), David Causer (1), Barry Page (1)
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Original Publication
Current Medical Research and Opinion
Vol. 14: 185-186, 1998
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Author Tag
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Publisher Tag
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Topic Tag
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#Valendar Turner
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#John M. Papadimitriou
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#David Causer
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#Barry Page
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#Current Medical Research and Opinion
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#HIV Tests
#ELISA
#Western Blot
#Viral Load
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At present it is accepted that in 1983 Montagnier proved the existence of HIV. In their 1983 study Montagnier and his colleagues took the supernatant from cultures containing tissue derived from AIDS patients and banded it in sucrose density gradients. They claimed that the 1.16 gm/ml band represented purified virus.(1) Some of the proteins and RNAs were considered to represent the retroviral proteins and retroviral genome respectively. Subsequently the proteins were used as antigens for the antibody tests and the nucleic acids for hybridisation and PCR studies. Indeed, it is logical that if the 1.16 gm/ml band contained purified viral-like particles and the particles were infectious, one has no choice but to consider both the proteins and the RNA as being viral constituents.
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Barré-Sinoussi F, Chermann JC, Rey F. (1983). Isolation of a T-Lymphotrophic Retrovirus from a patient at Risk for Acquired Immune Deficiency Syndrome (AIDS). Science 220:868-871
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Tahi D. (1998). Did Luc Montagnier discover HIV? Text of video interview with Professor Luc Montagnier at the Pasteur Institute July 18th 1997. Continuum 5:30-34