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Author | Eleni Papadopulos Valendar Turner John M. Papadimitriou David Causer Bruce Hedland-Thomas Barry Page
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Topic | CD4 Reliability T4 Cells T Lymphocytes Kaposi Sarcoma CD4 Decrease Haemophilia Blood Transfusions
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Summary | This is an excerpt from a critical analysis of the HIV-T4-CELL-AIDS hypothesis. The authors question the belief that a decrease in T4 cells is the hallmark of HIV infection and AIDS. They present evidence that challenges this hypothesis, such as healthy individuals having abnormal T4 cell counts and mice with low T4 cell numbers having prolonged life. The authors also highlight inconsistencies in T4 cell measurements and variations in AIDS cases based on different definitions. They argue that if T4 cell depletion is the cause of AIDS, all individuals with low T4 cell counts should have opportunistic infections, which is not the case. The authors conclude that further research is needed to fully understand the relationship between T4 cells and AIDS.
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Meta Tag | HIV-T4-CELL-AIDS Hypothesis T4 Cell Decrease AIDS Opportunistic Infections Neoplasms Blood Transfusion Thalassaemia Major Pulmonary Dysfunction CD4 Lymphocyte Determinations Kaposi's Sarcoma Cytotoxic Chemotherapy Systemic Lupus Erythematosus
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Eleni Papadopulos-Eleopulos,1 Valendar F.Turner,2 John M. Papadimitriou,3 David Causer,1 Bruce Hedland-Thomas,1 & Barry Page1
1: Department of Medical Physics, 2: Department of Emergency Medicine, Royal Perth Hospital, Perth, Western Australia; 3: Department of Pathology, University of Western Australia.
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Perth Group
Eleni Papadopulos
Valendar Turner
John M. Papadimitriou
David Causer
Bruce Hedland-Thomas
Barry Page
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T4 and the clinical syndrome
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